Research - Transformations with Sulfur and Fluorine
The Ball Laboratory is interested in developing new metal-catalyzed/-mediated organic reactions. Our focus is to develop methodologies to make and activate sulfur(VI) fluorides. In particular we are interested in using sulfur (VI) fluorides as a more air and water stable alternative to traditional synthesis of sulfur-based organic molecules. Our strategy is to achieve this goal by metal-catalyzed activation of sulfur(VI) fluorides via sulfur-fluorine exchange (SuFEx) to make sulfonylated compounds. Additionally, we have interest in sulfur (VI) fluorides in cross-coupling chemistry.
Our research involves a two-step strategy: 1) development of new catalytic reactions, and 2) mechanistic investigations of these reactions with model organometallic complexes. Experiments and results from each component facilitate the innovation in the other providing an impactful, deeper understanding of the chemistry. The goals of this research for students is to learn how to turn theory into practice, to critically work through scientific challenges, and to understand and take ownership of their work. Most importantly, I want students to appreciate and develop a love for science!
Students will gain extensive experience in organic and inorganic synthesis, metal catalysis, NMR spectroscopy, and physical organic chemistry. Students with a wide variety of interests are welcomed into our lab! Please explore the links below to learn more about the Ball Lab.
NIGMS NIH R15 AREA grant (R15GM134457) 2020-2023
Pomona College Start-up
Pomona College Summer Undergraduate Research Program
ACS PRF 2013-2018
Ball Lab Instrumentation